Fawn Dog
Because there are too many viruses and bacteria in the outside world, dogs who often go out and have poor immunity are easily exposed to these germs. Therefore, it is recommended that dogs be vaccinated regularly and widely Dog body disease resistance. However, some dogs are vaccinated according to the immunization program, but there will be times when immunity fails. So what are the reasons for immunity failure? What should you do to minimize the damage to your dog when encountering this situation?
1. Reasons for immune failure in dogs
1. Genetic factors
Animal body defects The immune response generated by vaccination is controlled by genetic factors to a certain extent. There are many different dog breeds and their immune responses are different. Even if different breeds of dogs have different immune responses to different vaccines, the immune responses of individual dogs are not uniform. Some dogs may even have genetic immune defects, leading to immune failure.
2. Maternal antibody disruption
This is one of the most common factors for immune failure. A certain level of maternal antibodies is extremely important in protecting puppies from early exposure to infectious diseases. However, due to the differences in the individual immune responses of breeding dogs and the differences in the vaccines used in breeding dogs (the developed maternal antibody titers also have large differences), the levels of maternal antibodies in puppies with different origins are uneven. If all puppies are vaccinated at the same age, puppies with too high maternal antibodies may disrupt the immune response of the vaccine, while puppies with too low maternal antibodies may be at risk of infectious diseases when vaccinated. Receptive period, which in turn leads to immune failure. Even if puppies from different breed bitches have different maternal antibody titers, they may not be completely consistent. If fixed first vaccination steps are taken, it will also disrupt the immune response of the vaccine and lead to immune failure.
3. Vaccine reasons
The use of vaccines produced by unofficial biological product factories, the quality of vaccines is substandard or of poor quality; the use of outdated vaccines; During transportation and storage, low temperature conditions cannot be maintained, which will reduce the vaccine titer; after the vaccine is taken out, it will be exposed to sunlight before immunization.Direct irradiation or taking out for too long will lead to a decrease in vaccine activity; the frozen vaccine is not diluted with a special diluent, and the diluted vaccine is not used up within the determined time, thus causing the safety of the vaccine to be greatly reduced; immunization is not done properly Inadequate vaccination, incorrect vaccination dose, etc. can affect the potency and immune efficacy of the vaccine, and even lead to the invalidation of immunity. < p > It is very important to maintain a high immune level and achieve good immune protection. Only with reasonable immunization procedures can effective vaccines produce good immune effects. The content of the immunization program includes vaccine type, first vaccination age, number of vaccinations, vaccination interval, etc. Factors such as the local epidemic and disease situation, the purpose of the dog, the breeding and control conditions, the level of maternal antibodies and the quality of the vaccine should be taken into consideration when formulating the immunization program. Among them, the level of maternal antibodies is the most critical. Improper immunization procedures, too early or too late primary vaccination, too long or too short interval between secondary immunizations, too many or too few vaccinations, etc., will affect the immune efficacy of the vaccine and lead to failure.
5. Nutritional factors
Antibodies enter the body and produce different levels of immune responses - cellular immunity and humoral immunity, both of which require certain Nutrients. Lack or deficiency of nutrients, especially vitamins A, D, B, E and various trace elements and full-price proteins, will affect the production speed or quantity of immune antibodies, thereby leading to delayed immune response or immune response ability. Whereabouts, guidance is immune to setbacks.
6. Hidden feelings
When the dog is vaccinated, it may have been in the dormant period of the disease, or has severe parasite symptoms. At this time, the disease often occurs in the near future after vaccination. Before all immune steps are completed, young and excitable animals growing up in a virus-infected environment are susceptible to disease.
7. Stress
The immune function of the animal body is controlled to a certain extent by nerves, body fluids and endocrine changes. Under the influence of stress factors such as cold (overheating), excessive humidity, poor ventilation, noise, sudden changes in environment, sudden changes in feed, etc., the secretion of adrenocortical hormones in the body decreases, which can significantly damage T lymphocytes and cause damage to macrophages. Suppresses the creation effect and reduces the synthesis and metabolism of IgG. Therefore, vaccination when the dog is in a period of acute stress response will weaken the dog's immune ability and lead to immune failure. This is why newly purchased puppies are particularly susceptible to illness.
Pet vaccines
2. Solutions to dog immune failure
1. Strengthen nutritional supplement
Strengthen feeding management, feed full-price synergistic dog food, pay attention to the supply of protein nutrition, and meet Supplement vitamins and a variety of trace elements, reduce various stress factors, rationally deworm, strengthen the body, and improve the dog's resistance and immunity to diseases.
2. Rational use of medication
Based on the nature and symptoms of the disease, as well as the severity of the disease, drugs should be used scientifically and rationally to avoid the abuse of drugs. It is best not to use disinfectants, antibiotics, and anti-coccidial drugs within a few days before and after vaccination. and antiviral drugs, and rationally use immune promoters such as levamisole, BCG, and interferons to enhance immune effects and be cautious in using glucocorticoids, cytotoxic drugs, and sex hormones to avoid damage to immune organs and immune cells. , Efficacy of immune response
Try not to go to a small pet store to vaccinate your dog. Try to choose a formal and certified animal hospital. The doctor there will consult you first about the dog’s recent condition. How is the dog's diet, infiltration, energy, etc., and then perform basic checks such as measuring body temperature, checking the condition of the visible mucous membrane, etc., to determine whether the dog meets the standards for vaccination, and then a scientific and reasonable immunization program can be formulated, and the doctor will also Things to note after disclosure of immune interruption
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